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GPR105 Antibody

GPR105 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPR105 Primary Polyclonal Antibody
Also known asGPR105 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPR105
SpecificityThis is a highly specific antibody against GPR105
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR105, GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, also designated P2Y14, and specifically co-localizes with astrocytes, is widely expressed throughout many brain regions where it localizes to glial cells, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names G protein coupled receptor for UDP-glucose, G protein-coupled receptor 105, G protein-coupled receptor VTR 15-20, G-protein coupled receptor 105, GPCR GPR105, GPR105, KIAA0001, P2RY14, P2Y purinoceptor 14, P2Y14, P2Y14 receptor, P2Y14 receptor, P2Y14_HUMAN, Purinergic receptor P2Y G protein coupled 14, Similar to TYPE-1 Angiotensin II receptor, UDP-glucose receptor, A330108O13Rik
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR105
Short nameGPR105 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPR105 (Antibody to)
Alternative techniqueantibodies
Identity 16442
Gene P2RY14
Long gene name purinergic receptor P2Y14
Synonyms gene GPR105
Synonyms gene name 14 , G protein-coupled receptor 105 purinergic receptor P2Y, G-protein coupled
Synonyms KIAA0001
Locus 3q25, 1
Discovery year 2001-09-27
GenBank acession D13626
Entrez gene record 9934
RefSeq identity NM_014879
Classification Purinergic receptors P2Y
Havana BLAST/BLAT OTTHUMG00000159859

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