Name : GPR105 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1128628133
| Long name | ALEXA FLUOR 555 Conjugated, GPR105 Polyclonal Antibody |
| Also known as | Anti-GPR105 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GPR105 |
| Specificity | This is a highly specific antibody against GPR105 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR105, GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, also designated P2Y14, and specifically co-localizes with astrocytes, is widely expressed throughout many brain regions where it localizes to glial cells, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | KIAA0001 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | GPR105 |
| Short name | GPR105 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, GPR105 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16442 |
| Gene | P2RY14 |
| Long gene name | purinergic receptor P2Y14 |
| Synonyms gene | GPR105 |
| Synonyms gene name | 14 , G protein-coupled receptor 105 purinergic receptor P2Y, G-protein coupled |
| Locus | 3q25, 1 |
| Discovery year | 2001-09-27 |
| GenBank acession | D13626 |
| Entrez gene record | 9934 |
| RefSeq identity | NM_014879 |
| Classification | Purinergic receptors P2Y |
| Havana BLAST/BLAT | OTTHUMG00000159859 |