GPR105 Antibody, Biotin Conjugated

GPR105 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, GPR105 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	GPR105
Specificity	This is a highly specific antibody against GPR105
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Subcellular location	Extracellular
Source	KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR105, GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, also designated P2Y14, and specifically co-localizes with astrocytes, is widely expressed throughout many brain regions where it localizes to glial cells, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation)
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	KIAA0001
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	GPR105 Conjugated
Short name	Conjugated, GPR105 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, GPR105 (Antibody to)
Alternative technique	antibodies
Identity	16442
Gene	P2RY14
Long gene name	purinergic receptor P2Y14
Synonyms gene	GPR105
Synonyms gene name	14 , G protein-coupled receptor 105 purinergic receptor P2Y, G-protein coupled
Locus	3q25, 1
Discovery year	2001-09-27
GenBank acession	D13626
Entrez gene record	9934
RefSeq identity	NM_014879
Classification	Purinergic receptors P2Y
Havana BLAST/BLAT	OTTHUMG00000159859

GPR105 Antibody, Biotin Conjugated

GPR105 Antibody, Biotin Conjugated size: 0.1ml 333

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