Name : GPR105 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4826899526
| Long name | Cy7 Conjugated, GPR105 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GPR105 |
| Specificity | This is a highly specific antibody against GPR105 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR105, GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, also designated P2Y14, and specifically co-localizes with astrocytes, is widely expressed throughout many brain regions where it localizes to glial cells, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | KIAA0001 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | GPR105 Conjugated |
| Short name | Conjugated, GPR105 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, GPR105 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16442 |
| Gene | P2RY14 |
| Long gene name | purinergic receptor P2Y14 |
| Synonyms gene | GPR105 |
| Synonyms gene name | 14 , G protein-coupled receptor 105 purinergic receptor P2Y, G-protein coupled |
| Locus | 3q25, 1 |
| Discovery year | 2001-09-27 |
| GenBank acession | D13626 |
| Entrez gene record | 9934 |
| RefSeq identity | NM_014879 |
| Classification | Purinergic receptors P2Y |
| Havana BLAST/BLAT | OTTHUMG00000159859 |