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GPR105 Antibody, Cy7 Conjugated

GPR105 Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, GPR105 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR105
SpecificityThis is a highly specific antibody against GPR105
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human G-protein coupled receptor 105
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR105, GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, also designated P2Y14, and specifically co-localizes with astrocytes, is widely expressed throughout many brain regions where it localizes to glial cells, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms KIAA0001
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetGPR105 Conjugated
Short name Conjugated, GPR105 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, GPR105 (Antibody to)
Alternative techniqueantibodies
Identity 16442
Gene P2RY14
Long gene name purinergic receptor P2Y14
Synonyms gene GPR105
Synonyms gene name 14 , G protein-coupled receptor 105 purinergic receptor P2Y, G-protein coupled
Locus 3q25, 1
Discovery year 2001-09-27
GenBank acession D13626
Entrez gene record 9934
RefSeq identity NM_014879
Classification Purinergic receptors P2Y
Havana BLAST/BLAT OTTHUMG00000159859

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