Name : GPR12 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2680314049
| Long name | GPR12 Primary Polyclonal Antibody |
| Also known as | GPR12 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GPR12 |
| Specificity | This is a highly specific antibody against GPR12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G protein coupled receptor 12 |
| Gene ID number | 2835 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR12 is a 334 amino acid peptide that is expressed primarily in brain, GPR12 is coupled to an inhibitory G protein, It positively influences differentiation and maturation of post-mitotic neurons, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, and it may promote the growth of neuronal precursor cells, particularly in regions where neuronal differentiation takes place, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FLJ97704, G protein coupled receptor 12, G-protein coupled receptor 12, GPCR GPR12, GPCR12, GPCR21, GPR 12, GPR12, GPR12_HUMAN, MGC138349, MGC138351, Probable G protein coupled receptor GPR12, FLJ18149 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GPR12 |
| Short name | GPR12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GPR12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4466 |
| Gene | GPR12 |
| Long gene name | G protein-coupled receptor 12 |
| Synonyms | GPCR21 PPP1R84 |
| Synonyms name | protein phosphatase 1, regulatory subunit 84 |
| Locus | 13q12, 13 |
| Discovery year | 1995-01-24 |
| GenBank acession | U18548 |
| Entrez gene record | 2835 |
| Pubmed identfication | 8262253 8530049 |
| Classification | Class A orphans , Protein phosphatase 1 regulatory subunits G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000016620 |