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GPR12 Antibody, FITC Conjugated

GPR12 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, GPR12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR12
SpecificityThis is a highly specific antibody against GPR12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human G protein coupled receptor 12
Gene ID number2835
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR12 is a 334 amino acid peptide that is expressed primarily in brain, GPR12 is coupled to an inhibitory G protein, It positively influences differentiation and maturation of post-mitotic neurons, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, and it may promote the growth of neuronal precursor cells, particularly in regions where neuronal differentiation takes place, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GPCR21 PPP1R84
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR12 Conjugated
Short name FITC Conjugated, GPR12 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GPR12 (Antibody to)
Alternative techniqueantibodies
Identity 4466
Gene GPR12
Long gene name G protein-coupled receptor 12
Synonyms name protein phosphatase 1, regulatory subunit 84
Locus 13q12, 13
Discovery year 1995-01-24
GenBank acession U18548
Entrez gene record 2835
Pubmed identfication 8262253 8530049
Classification Class A orphans , Protein phosphatase 1 regulatory subunits G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000016620

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