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GPR124/TEM5 Antibody, FITC Conjugated

GPR124/TEM5 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GPR124/TEM5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR124
SpecificityThis is a highly specific antibody against GPR124
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human G protein coupled receptor 124
Gene ID number25960
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1), TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies, TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis, TEM5 is a seven-pass transmembrane receptor, TEM7 and TEM8 span the membrane once, TEM7 is highly expressed in tumor endothelium and neurons, TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues, Therefore, These include TEM1 (endosialin), whereas TEM1, Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms TEM5 DKFZp434C211 DKFZp434J0911 KIAA1531 FLJ14390
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR124/TEM5 Conjugated
Short name FITC Conjugated, GPR124/TEM5 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GPR124/TEM5 (Antibody to)
Alternative techniqueantibodies
Identity 17849
Gene ADGRA2
Long gene name adhesion G protein-coupled receptor A2
Synonyms gene GPR124
Synonyms gene name G protein-coupled receptor 124
Synonyms name tumor endothelial marker 5
Locus 8p11, 23
Discovery year 2003-02-25
GenBank acession AB040964
Entrez gene record 25960
Pubmed identfication 11559528 12565841 25713288
Classification Immunoglobulin like domain containing Adhesion G protein-coupled receptors, subfamily A
Havana BLAST/BLAT OTTHUMG00000156182

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