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GPR17 Antibody, FITC Conjugated

GPR17 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GPR17 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR17
SpecificityThis is a highly specific antibody against GPR17
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human G protein coupled receptor 17
Gene ID number2840
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background GPR17, GPR17, GPR17 is thought to play a role in mediating neuronal death, In some neurons, Two named isoforms of GPR17 exist as a result of alternative splicing events, Upon brain injury, While GPR17 is expressed in kidney, a membrane receptor for uracil nucleotide and CysLTs, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), heart and umbilical vein endothelial cells, increase significantly at the site of damage, infiltrating the lesioned area, is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins, is upregulated as well, it is expressed in the highest levels in the brain, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, G protein-coupled receptor 17
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR17 Conjugated
Short name FITC Conjugated, GPR17 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, G protein-coupled receptor 17 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GPR17 and IDBG-639124 and ENSBTAG00000006261 and 782442, GPR17 and IDBG-69246 and ENSG00000144230 and 2840, Gpr17 and IDBG-133208 and ENSMUSG00000052229 and 574402, Plasma membranes, chemokine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity, this GO :0004950: chemokine receptor activity, G protein-coupled receptor 17
Identity 4471
Gene GPR17
Long gene name G protein-coupled receptor 17
Locus 2q14, 3
Discovery year 1995-11-21
Entrez gene record 2840
Pubmed identfication 8558062
Classification Class A orphans , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000131533

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