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GPR40 Antibody

GPR40 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPR40 Primary Polyclonal Antibody
Also known asGPR40 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPR40
SpecificityThis is a highly specific antibody against GPR40
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-190/300
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR40
Gene ID number2864
Swiss ProtO14842
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Fatty acid binding increases glucose-stimulated insulin secretion, Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, May also play a role in bone homeostasis, Seems to act through a G(q) and G(i)-mediated pathway, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1), leading to an increase of the intracellular calcium concentration, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity), G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FFAR1, Free fatty acid receptor 1, G-protein coupled receptor 40, GPCR40, GPR40, FFA1R
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR40
Short nameGPR40 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPR40 (Antibody to)
Alternative techniqueantibodies
Identity 4498
Gene FFAR1
Long gene name free fatty acid receptor 1
Synonyms gene GPR40
Synonyms gene name G protein-coupled receptor 40
Synonyms FFA1R
Locus 19q13, 12
Discovery year 1997-10-10
GenBank acession AF024687
Entrez gene record 2864
Pubmed identfication 15684720
RefSeq identity NM_005303
Classification Free fatty acid receptors
Havana BLAST/BLAT OTTHUMG00000188261

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