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GPR40 Antibody, FITC Conjugated

GPR40 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, GPR40 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR40
SpecificityThis is a highly specific antibody against GPR40
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range140-190/300
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human GPR40
Gene ID number2864
Swiss ProtO14842
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Fatty acid binding increases glucose-stimulated insulin secretion, Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, May also play a role in bone homeostasis, Seems to act through a G(q) and G(i)-mediated pathway, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1), leading to an increase of the intracellular calcium concentration, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity), G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FFA1R
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR40 Conjugated
Short name FITC Conjugated, GPR40 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GPR40 (Antibody to)
Alternative techniqueantibodies
Identity 4498
Gene FFAR1
Long gene name free fatty acid receptor 1
Synonyms gene GPR40
Synonyms gene name G protein-coupled receptor 40
Locus 19q13, 12
Discovery year 1997-10-10
GenBank acession AF024687
Entrez gene record 2864
Pubmed identfication 15684720
RefSeq identity NM_005303
Classification Free fatty acid receptors
Havana BLAST/BLAT OTTHUMG00000188261

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