Filters

GPR43 Antibody, ALEXA FLUOR 488

GPR43 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, GPR43 Polyclonal Antibody
Also known asAnti-GPR43 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPR43
SpecificityThis is a highly specific antibody against GPR43
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range63-84/330
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR43
Gene ID Number2867
Swiss ProtO15552
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Finally, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, In addition to SCFAs, In omnivorous mammals, In parallel to its role in energy homeostasis, Its activation results in the formation of inositol 1, May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils, May also regulate the production of LEP/Leptin, May play a role in glucose homeostasis by regulating the secretion of GLP-1, PubMed:12711604, PubMed:23589301), SCFAs serve as a source of energy but also act as signaling molecules, That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, a hormone acting on the central nervous system to inhibit food intake, and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity, in response to short-chain fatty acids accumulating in the intestine, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097), may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers, regulating the rapid production of chemokines and cytokines, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation, the short chain fatty acids (SCFAs), the short chain fatty acids acetate, 4, 5-trisphosphate, G protein-coupled receptor that is activated by a major product of dietary fiber digestion
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FFA2R
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GPR43 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGPR43
Short nameGPR43 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, GPR43 (Antibody to)
Alternative techniqueantibodies
Identity 4501
Gene FFAR2
Long gene name free fatty acid receptor 2
Synonyms gene GPR43
Synonyms gene name G protein-coupled receptor 43
Locus 19q13, 12
Discovery year 1997-10-10
GenBank acession AF024690
Entrez gene record 2867
Pubmed identfication 9344866
RefSeq identity NM_005306
Classification Free fatty acid receptors
Havana BLAST/BLAT OTTHUMG00000183303

Similar products

Subscribe to our Newsletter