Name : GPR49/LGR5 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7638775382
| Long name | GPR49/LGR5 Primary Polyclonal Antibody |
| Also known as | GPR49/LGR5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GPR49/LGR5 |
| Specificity | This is a highly specific antibody against GPR49/LGR5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 825-875/907 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse GPR49 |
| Gene ID number | 14160 |
| Swiss Prot | Q9Z1P4 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In contrast to classical G-protein coupled receptors, Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development, RSPO2, RSPO3 or RSPO4), Upon binding to R-spondins (RSPO1, associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, does not activate heterotrimeric G-proteins to transduce the signal, triggering the canonical Wnt signaling pathway to increase expression of target genes, Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | G-protein coupled receptor 49, Gpr49, Leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, Orphan G-protein coupled receptor FEX, FEX |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GPR49/LGR5 |
| Short name | GPR49/LGR5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GPR49/LGR5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4504 |
| Gene | LGR5 |
| Long gene name | leucine rich repeat containing G protein-coupled receptor 5 |
| Synonyms gene | GPR67 GPR49 |
| Synonyms gene name | G protein-coupled receptor 49 |
| Synonyms | HG38 FEX |
| Locus | 12q21, 1 |
| Discovery year | 1999-10-22 |
| GenBank acession | AF062006 |
| Entrez gene record | 8549 |
| Pubmed identfication | 9642114 |
| RefSeq identity | NM_003667 |
| Classification | Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000169543 |