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GPR56 (1443CT377.65.29) Monoclonal Antibody

GPR56 (1443CT377.65.29) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name29) Monoclonal Antibody, 65, GPR56 (1443CT377
Also known as29) Monoclonal Antibody, 65, GPR56 (1443CT377
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPR56
SpecificityThis is a highly specific antibody against GPR56
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1443CT377, 29, 65
SourceThis antibody is generated from a mouse immunized with a recombinant protein
Gene ID number9289
Swiss ProtQ9Y653
Tested Applications IF, WB
Recommended dilutions WB(1:1000), IF(1:25) , WB(1:1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ADGRG1 N-terminal fragment: Plays a critical role in cancer progression by activating VEGFA production and angiogenesis through a signaling pathway mediated by PRKCA (PubMed:21724588), Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662), Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells, Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity), Plays an essential role in testis development (By similarity), PubMed:21724588), Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity), Receptor involved in cell adhesion and probably in cell-cell interactions
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ADGRG1, Adhesion G-protein coupled receptor G1, BPPR, G-protein coupled receptor 56, GPR56, Protein TM7XN1, TM7LN4, TM7XN1, UNQ540/PRO1083, BFPP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target29) Monoclonal, 65, GPR56 (1443CT377
Short name29) Monoclonal Antibody, 65, GPR56 (1443CT377
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name29) monoclonal (Antibody to), 65, G protein-coupled receptor 56 (1443CT377
Alternative techniqueantibodies
Alternative to gene target BFPP and BPPR and TM7LN4 and TM7XN1, GPR56 and IDBG-33507 and ENSG00000205336 and 9289, Gpr56 and IDBG-183010 and ENSMUSG00000031785 and 14766, Plasma membranes, extracellular matrix binding, this GO :0001525 and angiogenesis and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010573 and vascular endothelial growth factor production and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021801 and cerebral cortex radial glia guided migration and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0035025 and positive regulation of Rho protein signal transduction and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070528 and protein kinase C signaling and biological process this GO :0097451 and glial limiting end-foot and cellular component this GO :2001223 and negative regulation of neuron migration and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0005518: collagen binding and also this GO :0050840: extracellular matrix binding, this GO :0004930: G-protein coupled receptor activity, this GO :0005518: collagen binding, this GO :0050840: extracellular matrix binding, G protein-coupled receptor 56
Identity 4512
Gene ADGRG1
Long gene name adhesion G protein-coupled receptor G1
Synonyms gene GPR56
Synonyms gene name G protein-coupled receptor 56
Synonyms TM7LN4 TM7XN1
Locus 16q21
Discovery year 1998-10-12
GenBank acession AJ011001
Entrez gene record 9289
Pubmed identfication 10049584 10100861 25713288
Classification Adhesion G protein-coupled receptors, subfamily G
Havana BLAST/BLAT OTTHUMG00000176742

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