Name : GPR71 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5888866915
| Long name | GPR71 Primary Polyclonal Antibody |
| Also known as | GPR71 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GPR71 |
| Specificity | This is a highly specific antibody against GPR71 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR71/T1R2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A controversial fifth taste, A family of G protein coupled receptors are involved in taste perception, Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG, Both pathways ultimately lead to neurotransmitter release, First, Sweet taste transduction is carried out by two pathways (2), T1R1, T1R2, The T1R family consists of three members, The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste, The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, The mouse T1R3 gene maps to chromosome 4 near the Sac locus, There are four widely accepted categories of taste perception, These proteins form heterodimers, a primary determinant of sweet preference in mice, and T1R3 (1-4), and T2R, and acesulfame-K (1â, and fungiform taste papillae, and includes T1R, and it is expressed in a subset of taste cells in circumvallate, and recognizes several sweet-tasting molecules, and sour, bitter, dulcin, foliate, has also been described, known as umami or monosodium glutamate (MSG), saccharin, salty, such as sucrose, sucrose and other sugars activate Gas via the T1Rs, sweet, which activates adenylyl cyclase to generate cAMP, which alters the selectivity of the subunits (1-4), which is involved in bitter taste perception, which is involved in sweet and umami taste perception, &euro, &ldquo, 4), The sense of taste provides animals with valuable information about the quality and nutritional value of food |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | G protein coupled receptor 71, G-protein coupled receptor 71, GPCR TAS1R2, GPR71, Sweet taste receptor T1R2, T1R2, TAS1R2, TR2, TS1R2_HUMAN, Taste receptor type 1 member 2, GPCR TAS1R2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GPR71 |
| Short name | GPR71 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GPR71 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14905 |
| Gene | TAS1R2 |
| Long gene name | taste 1 receptor member 2 |
| Synonyms gene | GPR71 |
| Synonyms gene name | G protein-coupled receptor 71 taste receptor, member 2 , type 1 |
| Synonyms | T1R2 TR2 |
| Locus | 1p36, 13 |
| Discovery year | 2001-03-21 |
| Entrez gene record | 80834 |
| Classification | Taste 1 receptors |
| Havana BLAST/BLAT | OTTHUMG00000002442 |