| Long name | GPX1 Primary Polyclonal Antibody |
| Also known as | GPX1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GPX1 |
| Specificity | This is a highly specific antibody against GPX1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 99-123/201 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse Glutathione Peroxidase 1 |
| Gene ID number | 14775 |
| Swiss Prot | P11352 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It contains a selenocysteine (Sec) residue at its active site, The 3' UTR of Sec-containing genes have a common stem-loop structure, The selenocysteine is encoded by the UGA codon, [provided by RefSeq], the sec insertion sequence (SECIS), which functions in the detoxification of hydrogen peroxide, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal, which normally signals translation termination, This gene product belongs to the family of glutathione peroxidase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI19524, AL33363, CGPx, Cellular glutathione peroxidase, GPx-1, GSHPx-1, Glutathione peroxidase 1, Gpx1, Selenium-dependent glutathione peroxidase 1, Gpx |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GPX1 |
| Short name | GPX1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | glutathione peroxidase 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | GPX1 and IDBG-305033 and ENSG00000233276 and 2876, GPXD and GSHPX1, Gpx1 and IDBG-199664 and ENSMUSG00000063856 and 14775, epigenetic and biological process this GO :0042311 and vasodilation and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043295 and glutathione binding and molecular function this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043534 and blood vessel endothelial cell migration and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045454 and cell redox homeostasis and biological process this GO :0047066 and phospholipid-hydroperoxide glutathione peroxidase activity and molecular function this GO :0048741 and skeletal muscle fiber development and biological process this GO :0051450 and myoblast proliferation and biological process this GO :0051593 and response to folic acid and biological process this GO :0051702 and interaction with symbiont and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060047 and heart contraction and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0061136 and regulation of proteasomal protein catabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, nuclei, phospholipid-hydroperoxide glutathione peroxidase activity, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001659 and temperature homeostasis and biological process this GO :0001885 and endothelial cell development and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0004602 and glutathione peroxidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0006144 and purine nucleobase metabolic process and biological process this GO :0006195 and purine nucleotide catabolic process and biological process this GO :0006629 and lipid metabolic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0006982 and response to lipid hydroperoxide and biological process this GO :0007568 and aging and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008283 and cell proliferation and biological process this GO :0008430 and selenium binding and molecular function this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0009609 and response to symbiotic bacterium and biological process this GO :0009611 and response to wounding and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009650 and UV protection and biological process this GO :0009725 and response to hormone and biological process this GO :0009749 and response to glucose and biological process this GO :0010269 and response to selenium ion and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014902 and myotube differentiation and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0018158 and protein oxidation and biological process this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019372 and lipoxygenase pathway and biological process this GO :0032355 and response to estradiol and biological process this GO :0033194 and response to hydroperoxide and biological process this GO :0033599 and regulation of mammary gland epithelial cell proliferation and biological process this GO :0035094 and response to nicotine and biological process this GO :0040029 and regulation of gene expression, this GO :0004602: glutathione peroxidase activity, this GO :0004602: glutathione peroxidase activity and also this GO :0005515: protein binding and also this GO :0008430: selenium binding and also this GO :0017124: SH3 domain binding and also this GO :0043295: glutathione binding and also this GO :0047066: phospholipid-hydroperoxide glutathione peroxidase activity, this GO :0005515: protein binding, this GO :0008430: selenium binding, this GO :0017124: SH3 domain binding, this GO :0043295: glutathione binding, this GO :0047066: phospholipid-hydroperoxide glutathione peroxidase activity, glutathione peroxidase 1 |
| Identity | 4553 |
| Gene | GPX1 |
| Long gene name | glutathione peroxidase 1 |
| Locus | 3p21, 31 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 2876 |
| Pubmed identfication | 9605859 |
| RefSeq identity | NM_000581 |
| Classification | Selenoproteins |
| Havana BLAST/BLAT | OTTHUMG00000156837 |
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