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GRAMD2 Antibody, Biotin Conjugated

GRAMD2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GRAMD2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGRAMD2
SpecificityThis is a highly specific antibody against GRAMD2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GRAMD2
Gene ID number196996
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region, Encoding more than 700 genes, In cases of Prader-Willi syndrome, In the case of Angelman syndrome, Marfan syndrome is associated with chromosome 15 through the FBN1 gene, Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation, which is encoded by chromosome 15, GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGRAMD2 Conjugated
Short name Conjugated, GRAMD2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GRAMD2 (Antibody to)
Alternative techniqueantibodies
Identity 27287
Gene GRAMD2
Long gene name GRAM domain containing 2
Locus 15q23
Discovery year 2005-11-02
GenBank acession AK002016
Entrez gene record 196996
Pubmed identfication 12477932
RefSeq identity NM_001012642
Classification GRAM domain containing
Havana BLAST/BLAT OTTHUMG00000172708

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