Name : Granzyme A Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4306185025
| Long name | Granzyme A Primary Polyclonal Antibody |
| Also known as | Granzyme A PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GZMA/Granzyme A |
| Specificity | This is a highly specific antibody against GZMA/Granzyme A |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 110-160/262 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Granzyme A |
| Gene ID number | 3001 |
| Swiss Prot | P12544 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity, Cleaves the nucleosome assembly protein SET after 'Lys-189', It cleaves after Lys or Arg, which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA, Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CTL tryptase, CTLA3, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, GZMA, Granzyme A, Granzyme-1, H factor, HF, Hanukkah factor, HFSP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Granzyme A |
| Short name | Granzyme A Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Granzyme A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4708 |
| Gene | GZMA |
| Long gene name | granzyme A |
| Synonyms gene | HFSP CTLA3 |
| Synonyms gene name | cytotoxic T-lymphocyte-associated serine esterase 3) , granzyme A (granzyme 1 |
| Synonyms name | CTL tryptase Cytotoxic T-lymphocyte-associated serine esterase-3 Hanukah factor serine protease) granzyme 1 |
| Locus | 5q11, 2 |
| Discovery year | 1988-05-31 |
| Entrez gene record | 3001 |
| Pubmed identfication | 3262682 3533635 |
| RefSeq identity | NM_006144 |
| Havana BLAST/BLAT | OTTHUMG00000097011 |