Name : Granzyme A Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6717994260
| Long name | ALEXA FLUOR 647 Conjugated, Granzyme A Polyclonal Antibody |
| Also known as | Anti-GZMA/Granzyme A PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GZMA/Granzyme A |
| Specificity | This is a highly specific antibody against GZMA/Granzyme A |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 110-160/262 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Granzyme A |
| Gene ID Number | 3001 |
| Swiss Prot | P12544 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity, Cleaves the nucleosome assembly protein SET after 'Lys-189', It cleaves after Lys or Arg, which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA, Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Granzyme A Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | Granzyme A |
| Short name | Granzyme A Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, Granzyme A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4708 |
| Gene | GZMA |
| Long gene name | granzyme A |
| Synonyms gene | HFSP CTLA3 |
| Synonyms gene name | cytotoxic T-lymphocyte-associated serine esterase 3) , granzyme A (granzyme 1 |
| Synonyms name | CTL tryptase Cytotoxic T-lymphocyte-associated serine esterase-3 Hanukah factor serine protease) granzyme 1 |
| Locus | 5q11, 2 |
| Discovery year | 1988-05-31 |
| Entrez gene record | 3001 |
| Pubmed identfication | 3262682 3533635 |
| RefSeq identity | NM_006144 |
| Havana BLAST/BLAT | OTTHUMG00000097011 |