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GRAP Antibody

GRAP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGRAP Primary Polyclonal Antibody
Also known asGRAP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGRAP
SpecificityThis is a highly specific antibody against GRAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRAP
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen For instance, GRB10 (also referred to as GRB-IR), GRB14 and Grap (for GRB2-related adapter protein), GRB7, Grap also associates with the Ras guanine nucleotide exchange factor Sos 1 via its amino terminal SH3 domain, Grap shares the highest degree of homology with GRB2 exhibiting 59% sequence identity with GRB2, Members include GRB2, Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific receptor sequences, The Grap SH2 domain is capable of binding to the activated stem cell factor receptor, While GRB10 and GRB14 are most closely related to GRB7, c-Kit and the erythropoietin receptor (EpoR), the GRB family of proteins lack a defined catalytic activity and are entirely composed of SH2 and SH3 domains, Many growth factors function by binding receptors with intrinsic tyrosine kinase activity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GRAP_HUMAN, GRB2 related adaptor protein, GRB2-related adapter protein, Growth factor receptor bound protein 2 related adaptor protein, MGC64880, OTTHUMP00000065766, Grap
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGRAP
Short nameGRAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGRAP (Antibody to)
Alternative techniqueantibodies
Identity 4562
Gene GRAP
Long gene name GRB2-related adaptor protein
Locus 17p11, 2
Discovery year 1998-09-29
GenBank acession U52518
Entrez gene record 10750
Pubmed identfication 8647802 8995379
RefSeq identity NM_006613
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000059436

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