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GRAP Antibody, ALEXA FLUOR 350

GRAP Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, GRAP Polyclonal Antibody
Also known asAnti-GRAP PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGRAP
SpecificityThis is a highly specific antibody against GRAP
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRAP
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen For instance, GRB10 (also referred to as GRB-IR), GRB14 and Grap (for GRB2-related adapter protein), GRB7, Grap also associates with the Ras guanine nucleotide exchange factor Sos 1 via its amino terminal SH3 domain, Grap shares the highest degree of homology with GRB2 exhibiting 59% sequence identity with GRB2, Members include GRB2, Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific receptor sequences, The Grap SH2 domain is capable of binding to the activated stem cell factor receptor, While GRB10 and GRB14 are most closely related to GRB7, c-Kit and the erythropoietin receptor (EpoR), the GRB family of proteins lack a defined catalytic activity and are entirely composed of SH2 and SH3 domains, Many growth factors function by binding receptors with intrinsic tyrosine kinase activity
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetGRAP
Short nameGRAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, GRAP (Antibody to)
Alternative techniqueantibodies
Identity 4562
Gene GRAP
Long gene name GRB2-related adaptor protein
Locus 17p11, 2
Discovery year 1998-09-29
GenBank acession U52518
Entrez gene record 10750
Pubmed identfication 8647802 8995379
RefSeq identity NM_006613
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000059436

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