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GRB7 Antibody

GRB7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGRB7 Primary Polyclonal Antibody
Also known asGRB7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGRB7
SpecificityThis is a highly specific antibody against GRB7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRB7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen GRB7, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6), GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6), Moreover, Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3, This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6, a SH2 domain protein, a central region with similarity to Ras GAP and a proline-rich N-terminus (5, has a single SH2 domain at its C-terminal, 2), 4), 6), 7), Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Epidermal growth factor receptor GRB 7, Epidermal growth factor receptor GRB-7, GRB7, GRB7 adapter protein, GRB7_HUMAN, Growth factor receptor bound protein 7, Growth factor receptor-bound protein 7, OTTHUMP00000164349, OTTHUMP00000164350, OTTHUMP00000164351, OTTHUMP00000164352, B47
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGRB7
Short nameGRB7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGRB7 (Antibody to)
Alternative techniqueantibodies
Identity 4567
Gene GRB7
Long gene name growth factor receptor bound protein 7
Synonyms gene name growth factor receptor-bound protein 7
Locus 17q12
Discovery year 1996-05-30
GenBank acession D43772
Entrez gene record 2886
RefSeq identity NM_005310
Classification Pleckstrin homology domain containing SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000133253

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