Name : GRB7 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7251078432
| Long name | Cy3 Conjugated, GRB7 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GRB7 |
| Specificity | This is a highly specific antibody against GRB7 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GRB7 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | GRB7, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6), GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6), Moreover, Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3, This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6, a SH2 domain protein, a central region with similarity to Ras GAP and a proline-rich N-terminus (5, has a single SH2 domain at its C-terminal, 2), 4), 6), 7), Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Properties | 1 of the GRB7 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GRB7 Conjugated |
| Short name | Conjugated, GRB7 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, GRB7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4567 |
| Gene | GRB7 |
| Long gene name | growth factor receptor bound protein 7 |
| Synonyms gene name | growth factor receptor-bound protein 7 |
| Locus | 17q12 |
| Discovery year | 1996-05-30 |
| GenBank acession | D43772 |
| Entrez gene record | 2886 |
| RefSeq identity | NM_005310 |
| Classification | Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133253 |