Name : GRM2+GRM4 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9575201258
| Long name | Biotin Conjugated, GRM2+GRM4 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GRM2+GRM4 |
| Specificity | This is a highly specific antibody against GRM2+GRM4 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GRM2+GRM4 |
| Gene ID number | 2912 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | GRM6, GRM7 and GRM8, Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions, Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C, Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities, Group II includes GRM2 and GRM3 while Group III includes GRM4, The metabotropic glutamate receptors are a family of G protein coupled receptors, and pharmacologic properties, putative signal transduction mechanisms, that have been divided into 3 groups on the basis of sequence homology, L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | GPRC1B mGlu2 MGLUR2 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GRM2+GRM4 Conjugated |
| Short name | Conjugated, GRM2+GRM4 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, GRM2+GRM4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4594 |
| Gene | GRM2 |
| Long gene name | glutamate metabotropic receptor 2 |
| Synonyms gene name | glutamate receptor, metabotropic 2 |
| Locus | 3p21, 2 |
| Discovery year | 1993-10-21 |
| GenBank acession | L35318 |
| Entrez gene record | 2912 |
| Pubmed identfication | 7620613 |
| Classification | Glutamate metabotropic receptors |
| Havana BLAST/BLAT | OTTHUMG00000156902 |