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GRM2+GRM4 Antibody, Biotin Conjugated

GRM2+GRM4 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GRM2+GRM4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGRM2+GRM4
SpecificityThis is a highly specific antibody against GRM2+GRM4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GRM2+GRM4
Gene ID number2912
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background GRM6, GRM7 and GRM8, Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions, Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C, Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities, Group II includes GRM2 and GRM3 while Group III includes GRM4, The metabotropic glutamate receptors are a family of G protein coupled receptors, and pharmacologic properties, putative signal transduction mechanisms, that have been divided into 3 groups on the basis of sequence homology, L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GPRC1B mGlu2 MGLUR2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGRM2+GRM4 Conjugated
Short name Conjugated, GRM2+GRM4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GRM2+GRM4 (Antibody to)
Alternative techniqueantibodies
Identity 4594
Gene GRM2
Long gene name glutamate metabotropic receptor 2
Synonyms gene name glutamate receptor, metabotropic 2
Locus 3p21, 2
Discovery year 1993-10-21
GenBank acession L35318
Entrez gene record 2912
Pubmed identfication 7620613
Classification Glutamate metabotropic receptors
Havana BLAST/BLAT OTTHUMG00000156902

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