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Group I mGLUR Antibody

Group I mGLUR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGroup I mGLUR Primary Polyclonal Antibody
Also known asGroup I mGLUR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGroup I mGLUR
SpecificityThis is a highly specific antibody against Group I mGLUR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range681-706/1194
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRM1
Gene ID number2911, 2915
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Alternative splicing results in multiple transcript variants encoding distinct isoforms, GRM6, GRM7 and GRM8, Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions, Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C, Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities, Group II includes GRM2 and GRM3 while Group III includes GRM4, The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system, The metabotropic glutamate receptors are a family of G protein-coupled receptors, [provided by RefSeq], and pharmacologic properties, putative signal transduction mechanisms, some of which may have distinct functions, that have been divided into 3 groups on the basis of sequence homology, L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GRM1_HUMAN, GRM5, GRM5_HUMAN, Glutamate Receptor Metabotropic 1, MGLUR5, mGluR1, mGlur5, MGLUR1, Metabotropic glutamate receptor 1, glutamate receptor metabotropic 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGroup I mGLUR
Short nameGroup I mGLUR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namefamily I mGLUR (Antibody to)
Alternative techniqueantibodies

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