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Group I mGLUR Antibody, ALEXA FLUOR 350

Group I mGLUR Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, Group I mGLUR Polyclonal Antibody
Also known asAnti-Group I mGLUR PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGroup I mGLUR
SpecificityThis is a highly specific antibody against Group I mGLUR
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range681-706/1194
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRM1
Gene ID Number2911, 2915
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alternative splicing results in multiple transcript variants encoding distinct isoforms, GRM6, GRM7 and GRM8, Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions, Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C, Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities, Group II includes GRM2 and GRM3 while Group III includes GRM4, The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system, The metabotropic glutamate receptors are a family of G protein-coupled receptors, [provided by RefSeq], and pharmacologic properties, putative signal transduction mechanisms, some of which may have distinct functions, that have been divided into 3 groups on the basis of sequence homology, L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms GRM1_HUMAN, GRM5, GRM5_HUMAN, Glutamate Receptor Metabotropic 1, MGLUR5, mGluR1, mGlur5, MGLUR1, Metabotropic glutamate receptor 1, glutamate receptor metabotropic 1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetGroup I mGLUR
Short nameGroup I mGLUR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, family I mGLUR (Antibody to)
Alternative techniqueantibodies

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