Name : GSK3 Alpha Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2072666635
| Long name | GSK3 Alpha Primary Polyclonal Antibody |
| Also known as | GSK3 Alpha PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GSK3 Alpha |
| Specificity | This is a highly specific antibody against GSK3 Alpha |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 70-120/483 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Mst2 |
| Gene ID number | 2931 |
| Swiss Prot | P49840 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | APC and AXIN1, CTNNB1/beta-catenin, Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis, Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease, In Wnt signaling, Is necessary for the establishment of neuronal polarity and axon outgrowth, May also mediate the development of insulin resistance by regulating activation of transcription factors, May be involved in the regulation of replication in pancreatic beta-cells, Regulates glycogen metabolism in liver, Requires primed phosphorylation of the majority of its substrates, Through phosphorylation of the anti-apoptotic protein MCL1, Wnt signaling and regulation of transcription factors and microtubules, but not in muscle, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), may control cell apoptosis in response to growth factors deprivation, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin, Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GSK-3 alpha, GSK3A, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase-3 alpha |
| Description | - or alpha protein sometimes glycoprotein present in blood, The GSK3 Alpha Antibody is a &alpha |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GSK3 Alpha |
| Short name | GSK3 Alpha Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GSK3 a (Antibody to) |
| Alternative technique | antibodies |