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GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody

GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGSK3 Alpha/Beta(Tyr279+Tyr216) Antibody
Also known asGSK3 Alpha/Beta(Tyr279+Tyr216) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGSK3 Alpha/Beta Tyr279+Tyr216
SpecificityThis is a highly specific antibody against GSK3 Alpha/Beta Tyr279+Tyr216
Modification(s)Phosphorylation
Modification site(s)Tyr279+Tyr216
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range250-300/483
Subcellular location Cell membrane, Nucleus
SourceKLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha/Beta around the phosphorylation site of Tyr279/Tyr216
Gene ID number29312932
Swiss ProtP49840
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APC and AXIN1, CTNNB1/beta-catenin, Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis, Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease, In Wnt signaling, Is necessary for the establishment of neuronal polarity and axon outgrowth, May also mediate the development of insulin resistance by regulating activation of transcription factors, May be involved in the regulation of replication in pancreatic beta-cells, Regulates glycogen metabolism in liver, Requires primed phosphorylation of the majority of its substrates, Through phosphorylation of the anti-apoptotic protein MCL1, Wnt signaling and regulation of transcription factors and microtubules, but not in muscle, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), may control cell apoptosis in response to growth factors deprivation, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin, Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GSK-3 alpha, GSK3A, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase-3 alpha
Description- or alpha protein sometimes glycoprotein present in blood, The GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody is a &alpha
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGSK3 Alpha/Beta(Tyr279+Tyr216)
Short nameGSK3 Alpha/Beta(Tyr279+Tyr216) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGSK3 a/b(Tyr279+Tyr216) (Antibody to)
Alternative techniqueantibodies

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