Filters

GTP binding protein REM1 Antibody

GTP binding protein REM1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGTP binding protein REM1 Antibody
Also known asGTP binding protein REM1 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGTP binding protein REM1
SpecificityThis is a highly specific antibody against GTP binding protein REM1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GTP binding protein REM1
Gene ID number28954
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, GEM/kir, It has been reported that the GTP-bound form of a related Ras-like GTPase, REM, REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms, The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane, There are data that suggest that REM similarly regulates Ca2+ channel expression, This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif, extended N- and C-termini, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle, unique effector domains, with a predicted molecular weight of 32, 9 kDa, REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E030011C07Rik, GD:REM, GES, GTP binding protein REM, GTP binding protein REM 1, GTP binding protein REM1, GTPase GES, GTPase regulating endothelial cell sprouting, MGC114556, MGC48669, OTTMUSP00000016855, RAS RAD and GEM like GTP binding, RAS like GTP binding, RAS like GTP binding protein REM, REM 1, REM1, REM1_HUMAN, RP23-35I8, Rad and Gem like GTP binding protein 1, 9, Rad and Gem related GTP binding protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGTP binding protein REM1
Short nameGTP binding protein REM1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGTP binding protein REM1 (Antibody to)
Alternative techniqueantibodies
Identity 15922
Gene REM1
Long gene name RRAD and GEM like GTPase 1
Synonyms gene REM
Synonyms gene name RAS (RAD and GEM)-like GTP-binding
Synonyms GES
Synonyms name GTPase GES
Locus 20q11, 21
Discovery year 2001-06-21
GenBank acession AF152863
Entrez gene record 28954
Pubmed identfication 10831614 14623965 22076634
RefSeq identity NM_014012
Classification RGK type GTPase family
Havana BLAST/BLAT OTTHUMG00000032168

Similar products

Subscribe to our Newsletter