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GTP binding protein REM1 Antibody, ALEXA FLUOR 647

GTP binding protein REM1 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, GTP binding protein REM1 Antibody
Also known asAnti-GTP binding protein REM1 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGTP binding protein REM1
SpecificityThis is a highly specific antibody against GTP binding protein REM1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GTP binding protein REM1
Gene ID Number28954
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, GEM/kir, It has been reported that the GTP-bound form of a related Ras-like GTPase, REM, REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms, The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane, There are data that suggest that REM similarly regulates Ca2+ channel expression, This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif, extended N- and C-termini, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle, unique effector domains, with a predicted molecular weight of 32, 9 kDa, REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms GES
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GTP binding protein REM1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetGTP binding protein REM1
Short nameGTP binding protein REM1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, GTP binding protein REM1 (Antibody to)
Alternative techniqueantibodies
Identity 15922
Gene REM1
Long gene name RRAD and GEM like GTPase 1
Synonyms gene REM
Synonyms gene name RAS (RAD and GEM)-like GTP-binding
Synonyms name GTPase GES
Locus 20q11, 21
Discovery year 2001-06-21
GenBank acession AF152863
Entrez gene record 28954
Pubmed identfication 10831614 14623965 22076634
RefSeq identity NM_014012
Classification RGK type GTPase family
Havana BLAST/BLAT OTTHUMG00000032168

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