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GTP binding protein REM1 Antibody, Cy7 Conjugated

GTP binding protein REM1 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, GTP binding protein REM1 Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGTP binding protein REM1
SpecificityThis is a highly specific antibody against GTP binding protein REM1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GTP binding protein REM1
Gene ID number28954
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, GEM/kir, It has been reported that the GTP-bound form of a related Ras-like GTPase, REM, REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms, The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane, There are data that suggest that REM similarly regulates Ca2+ channel expression, This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif, extended N- and C-termini, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle, unique effector domains, with a predicted molecular weight of 32, 9 kDa, REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms GES
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetGTP binding protein REM1 Conjugated
Short name Conjugated, GTP binding protein REM1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, GTP binding protein REM1 (Antibody to)
Alternative techniqueantibodies
Identity 15922
Gene REM1
Long gene name RRAD and GEM like GTPase 1
Synonyms gene REM
Synonyms gene name RAS (RAD and GEM)-like GTP-binding
Synonyms name GTPase GES
Locus 20q11, 21
Discovery year 2001-06-21
GenBank acession AF152863
Entrez gene record 28954
Pubmed identfication 10831614 14623965 22076634
RefSeq identity NM_014012
Classification RGK type GTPase family
Havana BLAST/BLAT OTTHUMG00000032168

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