Name : GTP cyclohydrolase 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7076319643
| Long name | GTP cyclohydrolase 1 Primary Polyclonal Antibody |
| Also known as | GTP cyclohydrolase 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GTP cyclohydrolase 1 |
| Specificity | This is a highly specific antibody against GTP cyclohydrolase 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GTP-CH-1 |
| Gene ID number | 2643 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions, Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, and tryptophan hydroxylases, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis, tyrosine, 8-dihydroneopterin triphosphate, GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DYT 5, DYT5, GCH, GCH 1, GCH1, GTP CH 1, GTP CH I, GTP cyclohydrolase 1, GTP cyclohydrolase 1 dopa responsive dystonia, GTP cyclohydrolase I, GTPCH 1, GTPCH1, Guanosine 5' triphosphate cyclohydrolase I, GTP-CH-1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GTP cyclohydrolase 1 |
| Short name | GTP cyclohydrolase 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GTP cyclohydrolase 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4193 |
| Gene | GCH1 |
| Long gene name | GTP cyclohydrolase 1 |
| Synonyms gene | GCH DYT5 DYT14 |
| Synonyms gene name | dystonia 14 |
| Synonyms | GTPCH1 DYT5a |
| Synonyms name | dopa-responsive dystonia |
| Locus | 14q22, 2 |
| Discovery year | 1988-05-11 |
| GenBank acession | U19523 |
| Entrez gene record | 2643 |
| Pubmed identfication | 7874165 8695054 |
| Havana BLAST/BLAT | OTTHUMG00000029754 |
| Locus Specific Databases | BIOMDBdb: Database of Mutations Causing BH4 Deficiencies and other PND |