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Guanylyl Cyclase alpha 1 Antibody, ALEXA FLUOR 350

Guanylyl Cyclase alpha 1 Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, Guanylyl Cyclase alpha 1 Antibody
Also known asAnti-Guanylyl Cyclase alpha 1 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGuanylyl Cyclase alpha 1
SpecificityThis is a highly specific antibody against Guanylyl Cyclase alpha 1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range330-380/690
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1
Gene ID Number2982
Swiss ProtQ02108
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both the alpha and beta subunits are required for cGMP generation, GCS, GCS is a heme containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The heme moeity mediates NO activation, The membrane-bound receptor forms, The soluble forms, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, a cGMP-synthesizing enzyme, act as receptors for nitric oxide, and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and one beta subunit, and this heme group also binds carbon monoxide, are peptide hormone receptors, consisting of one alpha subunit, designated GCS-alpha-1, is the major receptor for the neurotransmitter nitric oxide (NO), known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which weakly stimulates the enzyme, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms GC-SA3, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3, Guanylate cyclase soluble subunit alpha-3, MYMY6, Soluble guanylate cyclase large subunit, GUCA3
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetGuanylyl Cyclase alpha 1
Short nameGuanylyl Cyclase alpha 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Guanylyl Cyclase a 1 (Antibody to)
Alternative techniqueantibodies

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