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Guanylyl Cyclase alpha 1 Antibody, Cy3 Conjugated

Guanylyl Cyclase alpha 1 Antibody, Cy3 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy3 Conjugated, Guanylyl Cyclase alpha 1 Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGuanylyl Cyclase alpha 1
SpecificityThis is a highly specific antibody against Guanylyl Cyclase alpha 1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range330-380/690
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1
Gene ID number2982
Swiss ProtQ02108
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both the alpha and beta subunits are required for cGMP generation, GCS, GCS is a heme containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The heme moeity mediates NO activation, The membrane-bound receptor forms, The soluble forms, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, a cGMP-synthesizing enzyme, act as receptors for nitric oxide, and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and one beta subunit, and this heme group also binds carbon monoxide, are peptide hormone receptors, consisting of one alpha subunit, designated GCS-alpha-1, is the major receptor for the neurotransmitter nitric oxide (NO), known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which weakly stimulates the enzyme, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms GC-SA3, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3, Guanylate cyclase soluble subunit alpha-3, MYMY6, Soluble guanylate cyclase large subunit, GUCA3
Properties 1 of the Guanylyl Cyclase alpha 1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGuanylyl Cyclase alpha 1 Conjugated
Short name Conjugated, Guanylyl Cyclase alpha 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, Guanylyl Cyclase a 1 (Antibody to)
Alternative techniqueantibodies

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