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Guanylyl Cyclase alpha 2 Antibody

Guanylyl Cyclase alpha 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGuanylyl Cyclase alpha 2 Antibody
Also known asGuanylyl Cyclase alpha 2 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGuanylyl Cyclase alpha 2
SpecificityThis is a highly specific antibody against Guanylyl Cyclase alpha 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 2
Gene ID number2977
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both alpha and beta subunits are required for cGMP generation, GCS is a cGMP-synthesizing enzyme, GCS is a heme-containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, The heme moeity mediates NO activation, The membrane-bound receptor form, The soluble form, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, act as receptors for nitric oxide (NO), and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and this heme group also binds carbon monoxide (CO), are peptide hormone receptors, consisting of one alpha subunit and one beta subunit, known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which is the major receptor for the neurotransmitter nitric oxide, which weakly stimulates the enzyme, with predominant expression in kidney and liver, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GCS-alpha 2, GCYA2_HUMAN, GUC1A2, GUCSA2, GC SA2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGuanylyl Cyclase alpha 2
Short nameGuanylyl Cyclase alpha 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGuanylyl Cyclase a 2 (Antibody to)
Alternative techniqueantibodies

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