H2AFX (980CT1.5.5) Monoclonal Antibody

H2AFX (980CT1.5.5) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 211

Size 0.1ml

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Long name	5, 5) Monoclonal Antibody, H2AFX (980CT1
Also known as	5, 5) Monoclonal Antibody, H2AFX (980CT1
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	H2AFX
Specificity	This is a highly specific antibody against H2AFX
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	5, 5, 980CT1
Source	This H2AFX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human H2AFX
Gene ID number	3014
Swiss Prot	P16104
Tested Applications	IHC-P, WB
Recommended dilutions	WB(1:1000), IHC-P(1:25)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Purification method	This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	5, 5) Monoclonal, H2AFX (980CT1
Short name	5, 5) Monoclonal Antibody, H2AFX (980CT1
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	5, 5) monoclonal (Antibody to), H2AFX (980CT1
Alternative technique	antibodies
Identity	4739
Gene	H2AFX
Long gene name	H2A histone family member X
Synonyms gene	H2AX
Synonyms gene name	H2A histone family, member X
Locus	11q23, 3
Discovery year	1994-11-22
GenBank acession	X14850
Entrez gene record	3014
Pubmed identfication	8076949
RefSeq identity	NM_002105
Classification	Histones
Havana BLAST/BLAT	OTTHUMG00000166196

H2AFX (980CT1.5.5) Monoclonal Antibody

H2AFX (980CT1.5.5) Monoclonal Antibody size: 0.1ml 211

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