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H3-K4-HMTase SETD7 Antibody

H3-K4-HMTase SETD7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameH3-K4-HMTase SETD7 Primary Polyclonal Antibody
Also known asH3-K4-HMTase SETD7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenH3-K4-HMTase SETD7
SpecificityThis is a highly specific antibody against H3-K4-HMTase SETD7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7
Gene ID number80854
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also able to demethylated 'Lys-372' of p53/TP53 in vitro, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Has also methyltransferase activity toward non-histone proteins such as p53/TP53, Monomethylates 'Lys-189' of TAF10, Monomethylates 'Lys-372' of p53/TP53, Plays a central role in the transcriptional activation of genes such as collagenase or insulin, Recruited by IPF1/PDX-1 to the insulin promoter, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins, leading to activate transcription, leading to increase the affinity of TAF10 for RNA polymerase II, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation, Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names H3 K4 HMTase, H3-K4-HMTase SETD7, H4 lysine 4 specic, Histone H3 K4 methyltransferase, Histone H3 lysine 4 specic methyltransferase, Histone H3-K4 methyltransferase SETD7, Histone H4 K4 methyltransferase, Histone lysine N methyltransferase, Histone lysine N methyltransferase H3 lysine 4 specic SET7, Histone-lysine N-methyltransferase SETD7, KIAA1717, KMT7, Lysine N-methyltransferase 7, Lysine methyltransferase, OTTHUMP00000164543, OTTHUMP00000220049, SET 7, SET 7/9, SET 9, SET D7, SET domain containing lysine methyltransferase 7, SET domain containing protein 7, SET domain containing protein 8, SET domain-containing protein 7, SET7, SET7/9, SET9, SETD7_HUMAN, Setd7, FLJ21193
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetH3-K4-HMTase SETD7
Short nameH3-K4-HMTase SETD7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameH3-K4-HMTase SETD7 (Antibody to)
Alternative techniqueantibodies
Identity 30412
Gene SETD7
Long gene name SET domain containing lysine methyltransferase 7
Synonyms KIAA1717 SET7 SET7/9 Set9 KMT7
Locus 4q31, 1
Discovery year 2006-02-15
GenBank acession AB051504
Entrez gene record 80854
Pubmed identfication 11850410 11779497
RefSeq identity NM_030648
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000133385

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