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H3-K4-HMTase SETD7 Antibody, Biotin Conjugated

H3-K4-HMTase SETD7 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, H3-K4-HMTase SETD7 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenH3-K4-HMTase SETD7
SpecificityThis is a highly specific antibody against H3-K4-HMTase SETD7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7
Gene ID number80854
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also able to demethylated 'Lys-372' of p53/TP53 in vitro, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Has also methyltransferase activity toward non-histone proteins such as p53/TP53, Monomethylates 'Lys-189' of TAF10, Monomethylates 'Lys-372' of p53/TP53, Plays a central role in the transcriptional activation of genes such as collagenase or insulin, Recruited by IPF1/PDX-1 to the insulin promoter, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins, leading to activate transcription, leading to increase the affinity of TAF10 for RNA polymerase II, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation, Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KIAA1717 SET7 SET7/9 Set9 KMT7
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetH3-K4-HMTase SETD7 Conjugated
Short name Conjugated, H3-K4-HMTase SETD7 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, H3-K4-HMTase SETD7 (Antibody to)
Alternative techniqueantibodies
Identity 30412
Gene SETD7
Long gene name SET domain containing lysine methyltransferase 7
Locus 4q31, 1
Discovery year 2006-02-15
GenBank acession AB051504
Entrez gene record 80854
Pubmed identfication 11850410 11779497
RefSeq identity NM_030648
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000133385

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