Name : H3-K4-HMTase SETD7 Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN6999215127
| Long name | Cy5 Conjugated, H3-K4-HMTase SETD7 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | H3-K4-HMTase SETD7 |
| Specificity | This is a highly specific antibody against H3-K4-HMTase SETD7 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7 |
| Gene ID number | 80854 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Also able to demethylated 'Lys-372' of p53/TP53 in vitro, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Has also methyltransferase activity toward non-histone proteins such as p53/TP53, Monomethylates 'Lys-189' of TAF10, Monomethylates 'Lys-372' of p53/TP53, Plays a central role in the transcriptional activation of genes such as collagenase or insulin, Recruited by IPF1/PDX-1 to the insulin promoter, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins, leading to activate transcription, leading to increase the affinity of TAF10 for RNA polymerase II, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation, Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | KIAA1717 SET7 SET7/9 Set9 KMT7 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | H3-K4-HMTase SETD7 Conjugated |
| Short name | Conjugated, H3-K4-HMTase SETD7 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, H3-K4-HMTase SETD7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30412 |
| Gene | SETD7 |
| Long gene name | SET domain containing lysine methyltransferase 7 |
| Locus | 4q31, 1 |
| Discovery year | 2006-02-15 |
| GenBank acession | AB051504 |
| Entrez gene record | 80854 |
| Pubmed identfication | 11850410 11779497 |
| RefSeq identity | NM_030648 |
| Classification | Lysine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000133385 |