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Hamartin Antibody

Hamartin Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameHamartin Primary Polyclonal Antibody
Also known asHamartin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHamartin
SpecificityThis is a highly specific antibody against Hamartin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hamartin
Gene ID number7248
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion, Hamartin is present in most adult tissues with strong expression in brain, Tuberin and hamartin interact with each other forming a cystoplasmic complex, Two different genetic loci have been linked to TSC, and kidney, encodes a protein called hamartin, encodes a protein called tuberin and the other loci, heart, one of these loci, the tuberous sclerosis-2 gene (TSC2), tuberous sclerosis-1 gene (TSC1), Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LAM, TSC, TSC1, TSC1_HUMAN, Tsc1 gene, Tuberous sclerosis 1, Tuberous sclerosis 1 protein, kiaa0243, Hamartin
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHamartin
Short nameHamartin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHamartin (Antibody to)
Alternative techniqueantibodies
Identity 12362
Gene TSC1
Long gene name tuberous sclerosis 1
Synonyms gene TSC
Synonyms KIAA0243 LAM hamartin
Locus 9q34
Discovery year 1986-01-01
GenBank acession AF013168
Pubmed identfication 9242607 10806479
Havana BLAST/BLAT OTTHUMG00000020844
Locus Specific Databases TSC Mutation Database Tuberous sclerosis database LRG_486

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