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HAMSTER ANTI MOUSE BIM:FITC Antibody

HAMSTER ANTI MOUSE BIM:FITC Antibody size: 100ug 514

Supplier MBS MONO
Price 514
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asBIM
Other names BCL2-like 11 (apoptosis facilitator), Bcl-2-like protein 11, Bcl2 interacting mediator of cell death, Bcl2-interacting mediator of cell death, bcl-2-like protein 11, bcl2-L-11, bcl2-interacting mediator of cell death, bcl-2-like protein 11 isoform 3
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameBIM
Gene name synonimsN/A
Other gene names 1500006F24Rik, Bcl2-L-11, Bcl2l11, Bim, Bim, Bod, Bcl2l11
ClonalityMonoclonal
Immunoglobulin isotypeIgG
Clone151-149
Host organismHamster
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Bcl-XL and Bcl-w, Bim is a pro-apoptotic protein within the Bcl-2 family, Bim is known to interact with pro-survival proteins including Bcl-2, Bim is released from microtubules and mediates caspase-dependent apoptosis, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Upon certain apoptotic stimuli, also known as Bod, where it is maintained in an inactive conformation by phosphorylation or through binding to the microtubule-associated dynein motor complex, which functions within the intrinsic apoptosis pathway, BIM This item is specific for human Bcl-2 interacting mediator of cell death (Bim), _x000D_, _x000D__x000D_It is expressed in a variety of cell types
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetBIM:
Short nameHAMSTER ANTI MOUSE BIM:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameHAMSTER antibody to MOUSE BIM:fluorecein (Antibody to)
Alternative techniqueantibodies
Identity 994
Gene BCL2L11
Long gene name BCL2 like 11
Synonyms gene name BCL2-like 11 (apoptosis facilitator)
Synonyms BOD BimL BimEL BimS BIM
Locus 2q13
Discovery year 1999-12-10
GenBank acession AF032458
Entrez gene record 10018
Pubmed identfication 9731710 9430630
Classification BCL2 homology region 3 (BH3) only
Havana BLAST/BLAT OTTHUMG00000131256
Locus Specific Databases LRG_620

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