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HAMSTER ANTI MOUSE CD137 Antibody

HAMSTER ANTI MOUSE CD137 Antibody size: 0.25 miligrams 437

Supplier MBS MONO
Price 437
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD137
Other names 4-1BB ligand receptor, 4-1BB ligand receptor, CD137 antigen, T-cell antigen 4-1BB, T-cell antigen 4-1BB, Tumor necrosis factor receptor superfamily member 9, member 9, secreted CD137 antigen, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 9, tumor necrosis factor receptor superfamily member 9 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD137
Gene name synonimsN/A
Other gene names 4-1BB, A930040I11Rik, AA408498, AI325004, CDw137, Cd137, Cd137, ILA, Ila, Ly63, Ly63, Tnfrsf9, Tnfrsf9
ClonalityMonoclonal
Immunoglobulin isotypeIgG
Clone17B5
Host organismHamster
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Antibody cross-linking of CD137 on NK cells stimulates the secretion of IFN-gamma, CD137 is a potent costimulatory receptor for the growth and functional maturation of activated T-cells in the presence of T-cell receptor signal, CD137-mediated activation is distinct from and independent of CD28, CD25 expression and responsiveness to IL-2 and is associated with tumour activity, It is found on activated T-cells, NK cells, Signalling through CD137 triggers T-cell expansion, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone 17B5 may be used to block CD137-mediated T-cell proliferation, a member of the tumour necrosis factor superfamily, also known as 4-1BB ligand receptor, but not cytotoxicity, cellular proliferation, cytokine production and prevention of activation-induced death of effector T-cells, monocytes and dendritic cells, CD137 This item recognises mouse CD137
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD137
Short nameHAMSTER ANTI MOUSE CD137 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHAMSTER antibody to MOUSE CD137 (Antibody to)
Alternative techniqueantibodies
Identity 11924
Gene TNFRSF9
Long gene name TNF receptor superfamily member 9
Synonyms gene ILA
Synonyms gene name member 9 , tumor necrosis factor receptor superfamily
Synonyms CD137 4-1BB
Locus 1p36, 23
Discovery year 1996-06-12
GenBank acession L12964
Entrez gene record 3604
Pubmed identfication 8262389 8639902
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000001223

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