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HAMSTER ANTI MOUSE CD137:FITC Antibody

HAMSTER ANTI MOUSE CD137:FITC Antibody size: 0.025 miligrams 232

Supplier MBS MONO
Price 232
Size 0.025 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD137
Other names 4-1BB ligand receptor, 4-1BB ligand receptor, CD137 antigen, T-cell antigen 4-1BB, T-cell antigen 4-1BB, Tumor necrosis factor receptor superfamily member 9, member 9, secreted CD137 antigen, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 9, tumor necrosis factor receptor superfamily member 9 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD137
Gene name synonimsN/A
Other gene names 4-1BB, A930040I11Rik, AA408498, AI325004, CDw137, Cd137, Cd137, ILA, Ila, Ly63, Ly63, Tnfrsf9, Tnfrsf9
ClonalityMonoclonal
Immunoglobulin isotypeIgG
Clone17B5
Host organismHamster
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Antibody cross-linking of CD137 on NK cells stimulates the secretion of IFN-gamma, CD137 is a potent costimulatory receptor for the growth and functional maturation of activated T-cells in the presence of T-cell receptor signal, CD137-mediated activation is distinct from and independent of CD28, CD25 expression and responsiveness to IL-2 and is associated with tumour activity, It is found on activated T-cells, NK cells, Signalling through CD137 triggers T-cell expansion, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone 17B5 may be used to block CD137-mediated T-cell proliferation, a member of the tumour necrosis factor superfamily, also known as 4-1BB ligand receptor, but not cytotoxicity, cellular proliferation, cytokine production and prevention of activation-induced death of effector T-cells, monocytes and dendritic cells, CD137 This item recognises mouse CD137
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD137:
Short nameHAMSTER ANTI MOUSE CD137:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameHAMSTER antibody to MOUSE CD137:fluorecein (Antibody to)
Alternative techniqueantibodies
Identity 11924
Gene TNFRSF9
Long gene name TNF receptor superfamily member 9
Synonyms gene ILA
Synonyms gene name member 9 , tumor necrosis factor receptor superfamily
Synonyms CD137 4-1BB
Locus 1p36, 23
Discovery year 1996-06-12
GenBank acession L12964
Entrez gene record 3604
Pubmed identfication 8262389 8639902
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000001223

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