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HAMSTER ANTI MOUSE CD178:FITC Antibody

HAMSTER ANTI MOUSE CD178:FITC Antibody size: 100ug 359

Supplier MBS MONO
Price 359
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD178
Other names CD95 ligand, CD95 ligand, CD95-L, CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, FasL, Soluble Fas ligand, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6, generalized lymphoproliferative disease, member 6), membrane form, sFasL, soluble formAlternative name(s):Receptor-binding FasL ectodomain, tumor necrosis factor ligand superfamily member 6, tumor necrosis factor ligand superfamily member 6 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD178
Gene name synonimsN/A
Other gene names APL, APT1LG1, Apt1lg1, CD178, CD95-L, CD95-L, CD95L, Cd95l, Fas ligand, Fas-L, FasL, FasL ICD, Fasl, Faslg, Faslg, SPA, Tnfsf6, Tnfsf6, gld, gld, sFasL, Fasl
ClonalityMonoclonal
Immunoglobulin isotypeIgG
CloneMFL4
Host organismHamster
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The binding of CD178 to its receptor CD95 (Fas), The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses, _x000D__x000D_Clone MFL4 is reported to block CD178/CD95 induced apoptosis, a 40kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis, chemotherapeutic agents and viral infection, expressed by activated T cells and NK cells, heat shock, induces Fas-mediated apoptosis of target cells, otherwise known as Fas Ligand/ CD95L, which can be induced on a variety of cells by radiation, CD178 This item recognises both mouse and rat CD178
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD178:
Short nameHAMSTER ANTI MOUSE CD178:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameHAMSTER antibody to MOUSE CD178:fluorecein (Antibody to)
Alternative techniqueantibodies
Identity 11936
Gene FASLG
Long gene name Fas ligand
Synonyms gene APT1LG1 TNFSF6
Synonyms gene name member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily
Synonyms FasL CD178
Locus 1q24, 3
Discovery year 1994-12-09
GenBank acession U11821
Entrez gene record 356
Pubmed identfication 7826947 9022072
Classification Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000034841
Locus Specific Databases FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58

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