HAMSTER ANTI MOUSE CD278 Antibody

HAMSTER ANTI MOUSE CD278 Antibody size: 0.25 miligrams 437

Price 437

Size 0.25 miligrams

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Also known as	CD278
Other names	Activation-inducible lymphocyte immunomediatory molecule, Inducible T-cell costimulator, activation-inducible lymphocyte immunomediatory molecule, inducible T-cell co-stimulator, inducible T-cell costimulator, inducible costimulator, inducible T-cell costimulator
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	CD278
Gene name synonims	N/A
Other gene names	AILIM, AILIM, CD278, CVID1, ICOS, ICOS
Clonality	Monoclonal
Immunoglobulin isotype	IgG
Clone	4A, C398
Host organism	Hamster
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity	Clone C398, It enhances all the basic T cell responses to a foreign antigen, It is essential for the efficient interaction between B and T cells and is involved in antibody responses to T cell dependent antigens, It is expressed on activated T cells and resting memory T cells, It up-regulates the synthesis of interleukin-10, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a CD28-superfamily costimulatory molecule, also known as Inducible T cell costimulator or ICOS, but not interleukin-2 and prevents the apoptosis of pre-activated T cells, namely proliferation, secretion of lymphokines and up-regulation of molecules that mediate cell-cell interaction, /i>, 4A has been reported to costimulate T cell activation and proliferation <, CD278 This item recognises CD278, i>, in vitro<
Purification method	N/A
Form/Appearance	Purified (Purified IgG - liquid)
Concentration	IgG concentration 500ug/1000ul
Storage and shipping	If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:	Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP)
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene target	CD278
Short name	HAMSTER ANTI MOUSE CD278 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	HAMSTER antibody to MOUSE CD278 (Antibody to)
Alternative technique	antibodies
Identity	5351
Gene	ICOS
Long gene name	inducible T-cell costimulator
Synonyms	AILIM CD278
Synonyms name	activation-inducible lymphocyte immunomediatory molecule
Locus	2q33, 2
Discovery year	2000-02-29
GenBank acession	AB023135
Entrez gene record	29851
Pubmed identfication	9930702 10617205
RefSeq identity	NM_012092
Classification	CD molecules
Havana BLAST/BLAT	OTTHUMG00000132880
Locus Specific Databases	ICOSbase: Mutation registry for ICOS deficiency LRG_65

HAMSTER ANTI MOUSE CD278 Antibody

HAMSTER ANTI MOUSE CD278 Antibody size: 0.25 miligrams 437

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