Name : HAMSTER ANTI MOUSE CD61:Biotin Antibody
Supplier : MBS MONO
Price :249
SKU : GEN7194389284
| Also known as | CD61 |
| Other names | GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa, integrin beta 3, integrin beta-3, platelet gpIIIa, platelet membrane glycoprotein IIIa, integrin beta-3 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD61 |
| Gene name synonims | N/A |
| Other gene names | CD61, GP3A, GPIIIa, INGRB3, Itgb3, Itgb3 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG |
| Clone | 1, HM beta 3 |
| Host organism | Hamster |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity | CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively, Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, This particular antibody might cross react with speacies outside of the listed ones, a 90kD a type I membrane protein, fibronectin, granulocytes and endothelial cells, macrophages, monocytes, platelets, vitronectin and thrombospondin, von Willebrands factor (vWF), which is expressed primarily on megakaryocytes, CD61 This item recognises the murine integrin beta 3 subunit (CD61) |
| Purification method | N/A |
| Form/Appearance | Biotin (Purified IgG conjugated to Biotin - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Biotinylated |
| Gene target | CD61: |
| Short name | HAMSTER ANTI MOUSE CD61: Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | Biotin |
| Alternative name | HAMSTER antibody to MOUSE CD61:biotinilated (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6156 |
| Gene | ITGB3 |
| Long gene name | integrin subunit beta 3 |
| Synonyms gene | GP3A |
| Synonyms gene name | antigen CD61) , beta 3 (platelet glycoprotein IIIa, integrin |
| Synonyms | CD61 GPIIIa |
| Synonyms name | platelet glycoprotein IIIa antigen CD61 |
| Locus | 17q21, 32 |
| Discovery year | 1988-06-09 |
| Entrez gene record | 3690 |
| Pubmed identfication | 2454952 |
| RefSeq identity | NM_000212 |
| Classification | Integrin beta subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000171956 |
| Locus Specific Databases | LRG_481 |