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HAMSTER ANTI MOUSE DELTA-LIKE PROTEIN 1 Antibody

HAMSTER ANTI MOUSE DELTA-LIKE PROTEIN 1 Antibody size: 0.25 miligrams 437

Supplier MBS MONO
Price 437
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asDELTA-LIKE PROTEIN 1
Other names Delta-like protein 1, Drosophila Delta homolog 1, H-Delta-1, delta-like 1 (Drosophila), delta-like protein 1, drosophila Delta homolog 1, delta-like protein 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name DELTA1, DL1, DLL1, Delta, Delta1, H-Delta-1, DLL1
Gene name synonims DELTA1, DL1, DLL1, Delta, Delta1, H-Delta-1, DLL1
Other gene names DELTA1, DL1, DLL1, Delta, Delta1, H-Delta-1, DLL1
ClonalityMonoclonal
Immunoglobulin isotypeIgG
CloneHMD1-5
Host organismHamster
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity DLL1 plays an important role in B and T cell differentiation, DLL3 and DLL4, Delta-like protein 1 (DLL1), Jagged1 (CD339), Jagged2, Signaling through DLL1 and Notch 2 has been implicated in the development of marginal zone B cells (MZB), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Subsequent signal transduction then occurs through either the CSL-NICD-Mastermind complex cascade (canonical pathway), The canonical pathway inhibits the differentiation of stem cells or progenitor cells, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone HMD1-5 has been shown to cross-react with rat mast cell line RBL-2H3 in flow cytometry (Per, _x000D__x000D_DLL1 is widely expressed, _x000D__x000D_Ligation of Notch receptors by their specific ligands, _x000D__x000D_The Notch signaling pathway is an evolutionarily conserved pathway in multi-cellular organisms, and acts as a mediator of cell fate decisions during hematopoiesis, and associates with the scaffolding protein MAGI1 at adherens junctions on neuronal processes, and both tumor progression and suppression, and may play a role in cell-to-cell communication in mammalian embryos, cardiac and endocrine development, important during fundamental developmental and physiological processes, in embryonic somite formation and patterning, including regulation of cell fate decisions during neuronal, induces proteolysis of the receptors by ADAM-family metalloproteases and the gamma-secretase complex, on physically adjacent signal receiving cells, one of the five major ligands of the Notch signaling pathway, or NF-kappaB-NICD and CSL-NICD-Deltex complex signaling cascades (non-canonical pathway), releasing the Notch intracellular domain (NICD) to translocate to the nucleus, stem cell hematopoiesis, thymic T-cell development, which is activated through the binding of specific ligands to the Notch receptors Notch 1-4, which is vital for cell-cell communication, whilst the non-canonical pathway promotes differentiation, within the transmembrane domain, DELTA-LIKE PROTEIN 1 This item specifically recognises Delta-like protein 1 (DLL1)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Functional Assay (FA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetDELTA-LIKE PROTEIN 1
Short nameHAMSTER ANTI MOUSE DELTA-LIKE PROTEIN 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHAMSTER antibody to MOUSE DELTA-LIKE PROTEIN 1 (Antibody to)
Alternative techniqueantibodies

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