Name : HAMSTER ANTI MOUSE KLRG1:FITC Antibody
Supplier : MBS MONO
Price :365
SKU : GEN5097062586
| Also known as | KLRG1 |
| Other names | Killer cell lectin-like receptor subfamily G member 1, Mast cell function-associated antigen 2F1, killer cell lectin-like receptor subfamily G, killer cell lectin-like receptor subfamily G member 1, mast cell function-associated antigen 2F1, member 1, killer cell lectin-like receptor subfamily G member 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | KLRG1 |
| Gene name synonims | N/A |
| Other gene names | 2F1-Ag, Klrg1, MAFA, MAFA-L, Mafa, Klrg1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG |
| Clone | 2F1 |
| Host organism | Hamster |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity | It is expressed by activated CD8 T-cells and by a large proportion of natural killer (NK) cells, It is not found in the spleen, KLRG1 plays an inhibitory role on NK cells and T-cells by binding to their ligands, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T-cells expressing KLRG1 have greatly reduced proliferation potential, This particular antibody might cross react with speacies outside of the listed ones, bone-marrow-derived mast cells or peritoneal mast cells, brain or kidney and is not expressed on mast cell lines, but are not limited in their capacity to perform immediate effector cell functions, lymph nodes, such as the secretion of gamma interferon, testis, the mouse homolog of the rat mast cell function-associated antigen (MAFA), thymus, KLRG1 This item recognises mouse KLRG1 (killer cell lectin-like receptor G1) |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | KLRG1: |
| Short name | HAMSTER ANTI MOUSE KLRG1:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | member 1:fluorecein (Antibody to), HAMSTER antibody to MOUSE killer cellular lectin-like receptor subfamily G |
| Alternative technique | antibodies |
| Alternative to gene target | 2F1 and CLEC15A and MAFA and MAFA-2F1 and MAFA-L and MAFA-LIKE, KLRG1 and IDBG-17564 and ENSG00000139187 and 10219, KLRG1 and IDBG-639693 and ENSBTAG00000013640 and 100295672, Klrg1 and IDBG-185261 and ENSMUSG00000030114 and 50928, Plasma membranes, carbohydrate binding, member 1, this GO :0004872 and receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0050776 and regulation of immune response and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0030246: carbohydrate binding, this GO :0030246: carbohydrate binding, killer cell lectin-like receptor subfamily G |
| Identity | 6380 |
| Gene | KLRG1 |
| Long gene name | killer cell lectin like receptor G1 |
| Synonyms gene name | killer cell lectin-like receptor subfamily G, member 1 |
| Synonyms | MAFA 2F1 MAFA-L CLEC15A |
| Synonyms name | C-type lectin domain family 15, member A |
| Locus | 12p13, 31 |
| Discovery year | 1999-09-17 |
| GenBank acession | AF097358 |
| Entrez gene record | 10219 |
| Pubmed identfication | 9862378 9842918 16461340 16140789 |
| RefSeq identity | NM_005810 |
| Classification | Killer cell lectin like receptors C-type lectin domain family |
| Havana BLAST/BLAT | OTTHUMG00000168277 |