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HAO1 Antibody

HAO1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHAO1 Primary Polyclonal Antibody
Also known asHAO1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHAO1
SpecificityThis is a highly specific antibody against HAO1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GOX/HAO1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2-hydroxyacid oxidases, HAO1 is also able to convert glyoxylate to oxalate, HAO1 is localized to peroxisomes and aids in organic acid metabolism via 2-hydroxyacid oxidase activity, HAO1 is thought to play a role in the pathophysiology of hyperoxaluria type 1, HAO1 prefenentially oxidizes the substrate glycolate and also oxidizes other substrates, Hyperoxaluria type 1 is characterized by an accumulation of oxalate that is thought to lead to precipitates of calcium oxalate in kidneys which can be fatal, The oxidation of glycolate yields glyoxylate which is utilized for peroxisomal synthesis of glycine, a peroxisomal enzyme, are enzymes that require a flavin cofactor to oxidize 2-hydroxyacids to 2-ketoacids while reducing oxygen to hydrogen peroxide, including 2-hydroxy fatty acids as well as L-?hydroxy acids of moderately short chain lengths, leading to accumulation of glyoxylate, such as HAO1, which is caused by defects in AGXT, GOX is a 370 amino acid protein that is expressed in liver and pancreas
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GOX, GOX1, HAO1, HAOX1, HAOX1_HUMAN, Hydroxyacid oxidase 1, MGC142225, MGC142227, OTTHUMP00000030231, S 2 hydroxy acid oxidase, Glycolate oxidase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHAO1
Short nameHAO1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHAO1 (Antibody to)
Alternative techniqueantibodies
Identity 4809
Gene HAO1
Long gene name hydroxyacid oxidase 1
Synonyms gene GOX1
Synonyms gene name hydroxyacid oxidase (glycolate oxidase) 1
Synonyms GOX
Synonyms name glycolate oxidase 1
Locus 20p12, 3
Discovery year 1999-09-09
GenBank acession AL021879
Entrez gene record 54363
Pubmed identfication 9891009
Havana BLAST/BLAT OTTHUMG00000031841

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