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HAS3 Antibody, ALEXA FLUOR 594

HAS3 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, HAS3 Polyclonal Antibody
Also known asAnti-HAS3 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHAS3
SpecificityThis is a highly specific antibody against HAS3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HAS3
Gene ID Number3038
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both HAS1 and HAS2 synthesize high molecular-weight HA, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins, HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis, HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults, IFN-g markedly upregulates HAS3 mRNA, Specifically, The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, The extracellular matrix in most vertebrates express HA, The human HAS3 gene maps to chromosome 16q22, The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix, suggesting distinct functional roles of the three proteins, whereas HAS3 produces lower molecular weight HA, whereas TGF Beta downregulates HAS3 transcript levels, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1, 1, 3 and b-1, 4 glycosidic bonds, HAS1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetHAS3
Short nameHAS3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, HAS3 (Antibody to)
Alternative techniqueantibodies
Identity 4820
Gene HAS3
Long gene name hyaluronan synthase 3
Locus 16q22, 1
Discovery year 1996-10-18
GenBank acession BC021853
Entrez gene record 3038
Pubmed identfication 9169154 9083017
RefSeq identity NM_138612
Classification Glycosyltransferase family 2
Havana BLAST/BLAT OTTHUMG00000137562

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