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HAS3 Antibody, FITC Conjugated

HAS3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, HAS3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHAS3
SpecificityThis is a highly specific antibody against HAS3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HAS3
Gene ID number3038
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both HAS1 and HAS2 synthesize high molecular-weight HA, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins, HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis, HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults, IFN-g markedly upregulates HAS3 mRNA, Specifically, The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, The extracellular matrix in most vertebrates express HA, The human HAS3 gene maps to chromosome 16q22, The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix, suggesting distinct functional roles of the three proteins, whereas HAS3 produces lower molecular weight HA, whereas TGF Beta downregulates HAS3 transcript levels, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1, 1, 3 and b-1, 4 glycosidic bonds, HAS1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHAS3 Conjugated
Short name FITC Conjugated, HAS3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HAS3 (Antibody to)
Alternative techniqueantibodies
Identity 4820
Gene HAS3
Long gene name hyaluronan synthase 3
Locus 16q22, 1
Discovery year 1996-10-18
GenBank acession BC021853
Entrez gene record 3038
Pubmed identfication 9169154 9083017
RefSeq identity NM_138612
Classification Glycosyltransferase family 2
Havana BLAST/BLAT OTTHUMG00000137562

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